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Macronodular cirrhosis

Cirrhosis - Humpath

Macronodular cirrhosis definition of macronodular

Portal or nutritional cirrhosis is also called Laënnec's cirrhosis. Biliary cirrhosis is caused by intrahepatic bile-duct diseases that impede bile flow. Bile is formed in the liver and is carried by ducts to the intestines. Bile then helps digest fats in the intestines Cirrhosis can cause weakness, loss of appetite, easy bruising, yellowing of the skin (jaundice), itching, and fatigue. Diagnosis of cirrhosis can be suggested by history, physical examination and blood tests, and can be confirmed by liver biopsy. [medicinenet.com Macronodular cirrhosis, on the other hand, refers to cirrhosis that has irregular nodules. The nodules often have a variation higher than 3mm diameter. It can occur as a result of hepatitis C and B, primary biliary cholangitis, and deficiency in alpha-1 antitrypsin. Mixed cirrhosis, as you may have guessed, has mixed features Macronodular cirrhosis Fig.78 - MACRONODULAR CIRRHOSIS: Larger nodules separated by wider scars and irregularly distributed throughout the liver usually due to an infectious agent such as viral hepatitis which does not diffuse uniformly throughout the liver

Ultrasound liver

Macronodular Cirrhosis: Symptoms, Diagnosis and Treatment

Facts about Micronodular Cirrhosis to be Aware of - Fatty

Liver Cirrhosis - Loyola University Chicag

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar tissue known as fibrosis, due to damage caused by liver disease. Damage causes tissue repair and subsequent formation of scar tissue, which over time can replace normal functioning tissue leading to the impaired liver function of cirrhosis Macronodular cirrhosis, in which the majority of the nodules are larger than 3 mm, has also been called postnecrotic cirrhosis, posthepatitic cirrhosis, or multilobular cirrhosis. It is mainly the result of chronic hepatitis (Fig. 41.1C) The conversion from micro- to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow-up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis. In the initi Medical Definition of macronodular. : characterized by large nodules macronodular cirrhosis

To help keep your cirrhosis from getting worse, you can do the following. Do not drink alcohol or use illegal drugs. Talk with your doctor before taking. prescription medicines. prescription and over-the-counter sleep aids. over-the-counter medicines, including nonsteroidal anti-inflammatory drugs (NSAIDS) and acetaminophen nodular cirrhosis at entry (needle biopsy) and at autopsy. At the time of entry, there is an almost equal number of micro- and macronodular cases, i.e., 48 and 52%, respec- tively, while at autopsy the majority of the cases are macronodular (96%). Of the 75 cases with micronodular cirrhosis at entry, 68 had macronodular cirrhosis a Macrophages from macronodular cirrhotic livers produced higher amounts of nitric oxide but less superoxide anion radicals than the controls. DNA synthesis was 10-12-fold and 3-10-fold higher in macrophages from micronodular and macronodular cirrhotic livers, respectively, when compared with the age-matched controls

Cirrhosis. Micronodular cirrhosis. Macronodular cirrhosi

  1. g the liver margin (arrows). The contour bulge caused by the nodular regeneration may help to detect the lesions. (b) Intraoperative photograph of macronodular cirrhosis
  2. Hepatic Pathology. This is an example of a micronodular cirrhosis. The regenerative nodules are quite small, averaging less than 3 mm in size. The most common cause for this is chronic alcoholism. The process of cirrhosis develops over many years
  3. Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. As cirrhosis progresses, more and more scar tissue forms, making it difficult for the liver to function (decompensated cirrhosis )
  4. biliary cirrhosis, sclerosing cholangitis, drug-induced liver disease and chronic biliary obstruction. Other causes include a1-antitrypsin deficiency, severe steatohepatitis in the morbidly obese and Wilson's disease. The remaining 5-10% of patients with cirrhosis of the liver have no known cause, a condition termed cryptogenic cirrhosis. Over th
  5. The most common histologic classification of cirrhosis is micronodular, macronodular, and mixed forms. Each form may be seen at different stages of the disease. Risk factors. Chronic viral hepatitis. Alcohol. Drug toxicity. Autoimmune and metabolic liver diseases, including nonalcoholic fatty liver disease. Miscellaneous disorders
  6. Macronodular cirrhosis: Gross, natural color, external view of liver and very enlarged spleen (liver has variable size nodules up to about 2 cm) Macronodular cirrhosis: Gross, natural color, cut surface, large irregular bands of fibrosis with variable size liver cell nodules up to about 8 mm and all necrotic appears to be an end stage liver.

Cirrhosis occurring on chronic viral or autoimmune hepatitis or cirrhosis of Wilson may be of this aspect, but hemochromatosis and alcoholic cirrhosis may be macronodular (especially after the suspension of alcohol abuse). - Mixed cirrhosis: when macronodules and micronodules are present at the same time Fauerholdt L, Schlichting P, Christensen E, et al. Conversion of micronodular cirrhosis into macronodular cirrhosis. Hepatology 1983; 3:928. Van de Water J, Cooper A, Surh CD, et al. Detection of autoantibodies to recombinant mitochondrial proteins in patients with primary biliary cirrhosis In macronodular cirrhosis (post-necrotic cirrhosis), the nodules are larger than 3 mm. The mixed cirrhosis consists in a variety of nodules with different sizes. Microscopically, cirrhosis is characterized by regeneration nodules, surrounded by fibrous septa. In these nodules, regenerating hepatocytes are disorderly disposed Cryptogenic cirrhosis is a condition that impairs liver function. People with this condition develop irreversible liver disease caused by scarring of the liver (cirrhosis), typically in mid- to late adulthood. The liver is a part of the digestive system that helps break down food, store energy, and remove waste products, including toxins Macronodular Cirrhosis: Disease Bioinformatics Research of Macronodular Cirrhosis has been linked to Liver Cirrhosis, Hepatitis, Liver Diseases, Liver Neoplasms, Liver Carcinoma. The study of Macronodular Cirrhosis has been mentioned in research publications which can be found using our bioinformatics tool below

Macronodular liver cirrhosis, relative sparing of the caudate lobe, and moderate splenomegaly. Case Discussion Patient with a known case of Wilson disease (hepato-lenticular degeneration) was referred for evaluation of an abdominal mass The purpose of this study was to retrospectively analyze the morphologic changes of hepatitis C virus-related cirrhosis, which commonly show the macronodular type of cirrhosis histologically , in relation to the portal venous supply and hepatic venous drainage by using multidetector computed tomographic (CT) volumetry

Cirrhosis pathophysiology - wikidoc

Pathology Outlines - Cirrhosi

The conversion from micro- to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow-up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis In humans, one study reported that 68 of 75 patients with micronodular cirrhosis on biopsy had macronodular cirrhosis at autopsy, with a median conversion time of approximately 2 years.17 At least partial regression of human cirrhosis has been documented in treated patients having biliary obstruction,18 hemochromatosis,19-22 Wilson disease,23. A patient suffering from chronic active hepatitis with macronodular cirrhosis, positive for hepatitis B surface antigen (HBsAg), was treated with an orthotopic liver allograft. The HBs antigenemia, as measured with several precipitation tests and by complement fixation, became negative after transplantation and remained so for about 2½ months Cirrhosis of the liver (hepatic cirrhosis) is fibrosis of the liver tissue with abnormal nodule formation that structurally deforms the liver. It is the end stage of chronic liver disease and a common cause of death worldwide. This contributes to the two types of cirrhosis - micronodular cirrhosis and macronodular cirrhosis. Causes of. • A patient suffering from chronic active hepatitis with macronodular cirrhosis, positive for hepatitis B surface antigen (HB s Ag), was treated with an orthotopic liver allograft. The HB s antigenemia, as measured with several precipitation tests and by complement fixation, became negative after transplantation and remained so for about 2½ months. During the interval, very low titers of.

CT and MRI of Cirrhosis and its Mimics : American Journal

Macronodular Cirrhosis • In this type, nodules are larger, usually more than 3mm in diameter upto several centimeters. • Involvement is diffuse, but looks more irregular than Micronodular type 9 Ramya Deepthi P 10. Mixed type of cirrhosis • In this type, mixture of both 2 types are seen. Only few portal tracts and central veins are involved Do metabolic diseases cause micronodular or macronodular cirrhosis? Micronodular. Does viral hepatitis cause micronodular or macronodular cirrhosis? Macronodular. What two problems result from cirrhosis? Parenchymal failure and portal hypertension (but both of these conditions can exist independently of each other) Cirrhosis of liver without mention of alcohol. ICD-9-CM 571.5 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 571.5 should only be used for claims with a date of service on or before September 30, 2015. For claims with a date of service on or after October 1, 2015, use an equivalent ICD-10. Macronodular cirrhosis. 7 What are the features of micronodular cirrhosis. (2) Regenerating nodules are usually 8 What is micronodular cirrhosis caused by. (2) Chronic alcohol misuse or biliary tract disease. 9 What are the features of macronodular cirrhosis. (2 cirrhosis is a typical micronodular cirrhosis (3,4). In macronodular cirrhosis one or more nodules have a diameter greater than the simple acinus, and these may be ascribed either to a complex acinus (primary macronodular cirrhosis) or to hyperplasia of an orig- inal micronodule (secondary macronodular cirrho

The macronodular type of cirrhosis has also been termed coarsely nodular cirrhosis, postnecrotic or posthepatitic in type. Popper (1966) has distinguished two suibcategories of macronodular cirrhosis-postnecrotic and posthepatitic (Gall, 1960). The different anatomical types of cirrhosis are probably points along a continuu

Cirrhosis Radiology Reference Article Radiopaedia

The safety of intra-abdominal surgery in patients with cirrhosis: model for end-stage liver disease score is superior to Child-Turcotte-Pugh classification in predicting outcome. Arch Surg . 2005. Alcoholic fatty liver Alcoholic hepatitis Alcoholic cirrhosis; Fibrosis can be centrilobular, pericellular, or periportal. Nodules are usually <3 mm; this form of cirrhosis is referred to as micronodular With cessation of alcohol use, larger nodules may form, resulting in a mixed micronodular and macronodular cirrhosis but cirrhosis often makes them nodular due to the existence of numerous regeneration nodules. The as-pect of the hepatic edge will depend on the size of these regeneration nodules. The edge can be nodular and thin in cases of micronodular cirrhosis (Figure 1) or nodular and thick in cases of macronodular ci-rrhosis (Figure 2) In the 46 patients with nonalcoholic cirrhosis (41 macronodular and 1 micronodular cirrhosis; 4 primary biliary cirrhosis), PVP was significantly higher than was WHVP (25.8 2 6.2 vs. 21.7 f 6.8 mm Hg; p < 0.001);in 20 patients, PVP exceeded WHVP by more than 4 mm Hg, and the mean difference was 7.5 mm Hg

Short description: CIRRHOSIS OF LIVER NOS. ICD-9-CM 571.5 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 571.5 should only be used for claims with a date of service on or before September 30, 2015. For claims with a date of service on or after October 1, 2015, use an equivalent ICD-10-CM code (or codes) In humans, one study reported that 68 of 75 patients with micronodular cirrhosis on biopsy had macronodular cirrhosis at autopsy, with a median conversion time of approximately 2 years.[17] At least partial regression of human cirrhosis has been documented in treated patients having biliary obstruction,[18] hemochromatosis,[19-22] Wilson disease,[23,24] intestinal bypass-related cirrhosis,[25. The conversion from micro‐ to macronodular cirrhosis is claimed to be a general phenomenon. In this study, the conversion was quantitated by means of liver needle follow‐up biopsies and autopsy in 156 patients followed in a controlled clinical trial of prednisone treatment in cirrhosis Hepatomegaly & Postnecrotic Macronodular Cirrhosis Symptom Checker: Possible causes include Chronic Alcoholism. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search

Cirrhosis of the liver: Life expectancy and stage

  1. Synonyms for macronodular cirrhosis in Free Thesaurus. Antonyms for macronodular cirrhosis. 1 synonym for cirrhosis: cirrhosis of the liver. What are synonyms for macronodular cirrhosis
  2. •Continued loss of hepatocytes and fibrosis results in cirrhosis, with fibrous septa and hepatocyte regenerative nodules. • This pattern of cirrhosis is characterized by irregularly sized nodules separated by variable but mostly broad scars. • The nodules are typically greater than 0.3 cm in diameter, earning the term macronodular cirrhosis. • While such cirrhosis is characteristic of.
  3. Start studying Gastrointesitnal - Pathology Lab #8 (cirrhosis). Learn vocabulary, terms, and more with flashcards, games, and other study tools
  4. macronodular cirrhosis cirrhosis in which regenerative nodules are more than 3 mm in diameter, seen most often following subacute hepatic necrosis due to toxic or viral hepatitis. The reticulin framework of normal lobules collapses and may be replaced by broad bands of fibrous tissue separating regenerative nodules of various sizes. Called also multilobular c., periportal c., postnecrotic c.
  5. Macronodular cirrhosis (irregular nodules with a variation greater than 3 mm in diameter): Cirrhosis due to hepatitis B and C, alpha-1 antitrypsin deficiency, and primary biliary cholangitis. Mixed cirrhosis (when features of both micronodular and macronodular cirrhosis are present): Usually, micronodular cirrhosis progresses into macronodular.
  6. al hepatic venules. Broad fibrous bands of varying thickness surround the nodules. Collapse of the normal liver architecture is suggested by the concentration of portal tracts within the.

Macronodular cirrhosis is characterized by larger nodules, which can measure several centimeters in diameter and may contain central veins (eFigure 16-18). This form corresponds more or less to postnecrotic (posthepatitic) cirrhosis but does not necessarily follow episodes of massive necrosis and stromal collapse Here's a liver with macronodular cirrhosis being observed in a surgery! Liver cirrhosis is an end result of an underlying pathology. It develops when scar tissue replaces the normal, healthy tissue of the liver Macronodular Mixed Micronodular cirrhosis is characterized by nodules that are less than 3mm in diameter Macronodular cirrhosis is characterized by nodules that are more than 3mm in diameter Micronodular cirrhosis can often progress into macronodular cirrhosis. During this transformation, a mixed form of cirrhosis may be seen. Causes: Alcoho

Macronodular cirrhosis (Concept Id: C2004456

Macronodular cirrhosis - caused by chronic hepatitis B or C or by autoimmune hepatitis. Pigment cirrhosis - Caused by hemochromatosis (iron accumulation) or Wilson disease (copper accumulation). Biliary cirrhosis - Caused by damage to the biliary tree; Hepatic failure and cirrhosis, but the precise nature ofthe associa-Fig. 1 Fig. 2 Fig. 1 Cirrhosis with amicronodularpattern in amiddle-agedmalealcoholic; nearly all the nodules are less than 3 mminsize (indicatedbyscale). Fig. 2 Cirrhosis with amacronodularpattern in an elderly man with ahistory ofhepatitis manyyears before Cirrhosis isn't curable, but it's treatable. Doctors have two main goals in treating this disease: Stop the damage to your liver, and prevent complications.. Alcohol abuse, hepatitis, and fatty. Micro Vs Macronodular Cirrhosis. If you are to be avoided though these organs which occurs mainly in patients with liver sarcoidosis also a cupcake cooking patterns and collagen formation your liver is one of the hepatic steatosis - abnormal greenish-brown in color. The Phytonutrient antioxidants that have been caused by an extended amount.

The nodules are surrounded by fibrous septa and may be small (i.e., <3 mm across—micronodular cirrhosis), large (>3 mm—macronodular cirrhosis), or of mixed size (mixed macro- and micronodular. Margins that are smooth or deformed by multiple small nodules are typical for micronodular cirrhosis, whereas a coarse nodularity of the margin is the result of macronodular cirrhosis. However, lobular livers are usually the resullt of marked subsegmental atrophy and hypertrophy rather than of large regenerative nodules (1)

KMU Pathology Lab《Slide 21

Macronodular cirrhosis (of liver) Micronodular cirrhosis (of liver) Mixed type cirrhosis (of liver) Portal cirrhosis (of liver) Postnecrotic cirrhosis (of liver) Index to Diseases and Injuries. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following. macronodular cirrhosis - Humpath.com - Human pathology. Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver > macronodular cirrhosis

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  1. In micronodular cirrhosis, the nodules are relatively small. If there are large nodules that type is identified as the macronodular cirrhosis. In some instances, it is possible to have both large and small nodules together in a cirrhotic liver. That form of cirrhosis is called the mixed type cirrhosis
  2. This is the case of macronodular cirrhosis (more frequent in HBV infection, but also in other liver diseases) where the nodules are surrounded by fine fibrous septa, which do not increase the liver stiffness to cirrhotic levels. 6.6.1 Portal hypertension screening
  3. ed; deep cicatricial connective tissue grayish-white retraction between nodes; the newly formed nodes are bright red, and the previously formed knots are brownish in color
  4. ICD-10-CM Code. K74.69. Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis. K74.69 is a billable ICD code used to specify a diagnosis of other cirrhosis of liver. A 'billable code' is detailed enough to be used to specify a medical diagnosis
  5. Macronodular pattern: Most nodules in this type of cirrhosis are larger than 3 mm in size, with the size varying considerably, and some nodules being several centimeters in size. Nodules in this type of cirrhosis may contain portal tracts and central veins, although their relationship to each other is not maintained architecturally
  6. Cirrhosis is an advanced stage of liver fibrosis characterized by. Distortion of hepatic architecture associated with vascularized fibrotic septa surrounding islands of regenerating hepatocyte nodules. Development of intrahepatic porto-hepatic and arterio-venous shunts within the fibrotic septa
Micronodular Cirrhosis Causes

Macronodular cirrhosis - definition of macronodular

  1. Cirrhosis. Friday 30 May 2003. Digital cases HPC:403: Cirrhosis in glycogen storage disease type 4 (GSD4) HPC:404: Cirrhosis after parenteral nutrition HPC:410: Cirrhosis in protracted exclusive parenteral nutrition. Variants. macronodular cirrhosis micronodular cirrhosis
  2. macronodular cirrhosis hepatocellular carcinoma 40 3 149 66 F Liver micronodular cirrhosis hepatocellular carcinoma 42 3 150 65 F Liver macronodular cirrhosis hepatocellular carcinoma 43 3 151 64 M Liver macro- and micronodular cirrhosis hepatocellular carcinoma 46 3 152 54
  3. Types of cirrhosis: 1.Nutritional and Alcoholic Cirrhosis.chronic alcoholism or prolonged severe malnutrition lead to steatosis fallowed by gradual progressive liver cells loss and cirrhosis. 2.Post hepatic Cirhosis.It fallows chronic active hepatitis.It is a mixed micro and macronodular cirrhosis
  4. A patient suffering from chronic active hepatitis with macronodular cirrhosis, positive for hepatitis B surface antigen (HBsAg), was treated with an orthotopic liver allograft. The HBs antigenemia, as measured with several precipitation tests and by complement fixation, became negative after transplantation and remained so for about 2 1/2 months
  5. The availability of computed tomographs (CTs) throughout the patient's course showed the development of macronodular cirrhosis as the patient's hepatic tumor burden increased. REPORT OF A CASE The patient was a 38-year-old woman who had a mastectomy in 1996 for infiltrating ductal carcinoma of the breast
  6. Wanless et al. demonstrated a histologic continuum from micronodular cirrhosis to macronodular cirrhosis and to ISC, and convincingly showed that ISC often represents regressed cirrhosis. Regression of fibrosis occurring in earlier stages of chronic liver diseases may result in normal-appearing hepatic parenchyma

Hepatic Pathology - University of Uta

K70.30 Alcoholic Cirrhosis of liver w/o ascites K70.31 Alcoholic Cirrhosis of liver w/ ascites K74.60 Unspecified Cirrhosis of liver Cirrhosis (of liver) NOS K74.69 Other Cirrhosis of liver • Cryptogenic Cirrhosis (of liver) • Macronodular Cirrhosis (of liver) • Micronodular Cirrhosis (of liver) • Mixed type Cirrhosis (of liver portal cirrhosis Laënnec's c. posthepatitic cirrhosis a type (usually macronodular) that is a sequel to acute hepatitis. postnecrotic cirrhosis macronodular c. Primary sclerosing cholangitis (PSC) is a chronic, or long-term, disease that slowly damages the bile ducts inside and outside the liver Ultrasound images appearances of cirrhosis In cirrhosis bands of fibrous tissue are laid down in the liver parenchyma between the hepatic lobules. This distorts and destroys the normal architecture of the liver, separating it into nodules. The process may be micronodular, which gives a generally coarse echotexture, or macronodular in which.

Cirrhosis - Hepatic and Biliary Disorders - Merck Manuals

571.5 is a legacy non-billable code used to specify a medical diagnosis of cirrhosis of liver without mention of alcohol. This code was replaced on September 30, 2015 by its ICD-10 equivalent. ICD-9: 571.5 Cirrhosis is a condition caused by chronic damage to the liver, most commonly due to. excessive alcohol consumption. , nonalcoholic fatty liver disease. , or. hepatitis C. infection. Other causes may include inflammatory or metabolic diseases, such as. primary biliary cirrhosis

Micronodular cirrhosis definition of micronodular

Pathology. At autopsy the liver weighed 2530g (normal ± 1500g). It is diffusely riddled with nodules, compatible with cirrhosis. On the cut surface it can be seen that the nodules are mostly >3mm and up to 1cm in size, so this is predominantly a macronodular cirrhosis The value of resection for patients with hepatitis B virus-related macronodular cirrhosis, however, remains unknown because of potentially fatal complications of this procedure. METHODS: Clinicopathological data were analyzed for 85 resected HCC patients with hepatitis B virus-related macronodular cirrhosis An end-stage complication of cirrhosis is the development of hepatocellular carcinoma (HCC). In fact, cirrhosis is the strongest risk factor for development of HCC, with approximately 80% of all HCCs associated with cirrhotic livers. 10 For patients with cirrhosis (of any cause), imaging plays a large role in surveillance and management. As. Cirrhosis is the severe scarring of the liver. With this, you have greater chances of having portal hypertension. This happens when there is increased pressure of the portal vein, therefore possibly causing hemorrhages of the esophageal varices. Ascites is a buildup of fluid in the abdomen. Hepatic encephalopathy is severe brain fog caused by. metabolic cirrhosis a type associated with metabolic diseases, such as hemochromatosis, Wilson's disease, glycogen storage disease, galactosemia, and disorders of amino acid metabolism. portal cirrhosis Laënnec's c. posthepatitic cirrhosis a type (usually macronodular) that is a sequel to acute hepatitis. postnecrotic cirrhosis macronodular c

Chronic hepatitis and liver cirrhosis Radiology Ke

Macronodular cirrhosis Characterized by nodules of variable sizes, some containing large areas of intact or regenerating parenchyma within each large nodule. Mixed macronodular & micronodular cirrhosis Vigorous regrowth in a previous micronodular cirrhosis Fig2.1 [x37] N - Nodular masses of Regenerated cells F - Fibrous tissue which surrounds the Objective Patients with hepatocellular carcinoma (HCC) presenting with nonmicronodular or micronodular cirrhosis are usually treated by hepatectomy. The value of resection for patients with hepatitis B virus-related macronodular cirrhosis, however, remains unknown because of potentially fatal complications of this procedure. Methods Clinicopathological data were analyzed for 85 resected HCC.

Micronodular cirrhosis (Concept Id: C0267812

Corticotropin-independent macronodular adrenal hyperplasia can lead to excess cortisol secretion and Cushing's syndrome. 1,2 Adrenocortical nodules in corticotropin-independent macronodular. In macronodular cirrhosis hepatocytes of hypertrophic type, rich in cell organelles, can be distinguished ultrastructurally from those with signs of atrophy and degeneration. Immediately after isolation many hepatocytes isolated from macronodular cirrhosis showed plasma membrane blebbing. Whereas the blebbing was without recognizable effects on. CIRRHOSIS Fibrosis, a hallmark of CH, is defined as a detectable deposit of extracellular matrix (ECM). Cirrhosis is the end stage of CH and is defined as a diffuse process character-ized by fibrosis of the liver and the conversion of normal liver architecture into structurally abnormal nodules, micro- or macronodular.1 Cirrhosis is the result.

Cirrhosis and Its Complications - Cirrhosis - Pocket DrugCirrhosis